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SIRPB1 抗体

This anti-SIRPB1 antibody is a 小鼠 单克隆 antibody detecting SIRPB1 in FACS. Suitable for 人.
产品编号 ABIN6559824
发货至: 中国

Quick Overview for SIRPB1 抗体 (ABIN6559824)

抗原

See all SIRPB1 抗体
SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

适用

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宿主

  • 33
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小鼠

克隆类型

  • 34
  • 5
单克隆

标记

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This SIRPB1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

B4B6
  • 原理

    Anti-Hu CD172b Purified

    特异性

    The mouse monoclonal antibody B4B6 recognizes an extracellular epitope of CD172b, an approximately 50 kDa transmembrane glycoprotein expressed on myeloid cells.

    交叉反应 (详细)

    Human

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    NIH-3T3 cells transfected with human CD172b

    亚型

    IgG1
  • 应用备注

    Flow cytometry: Recommended dilution: 1-4 μg/mL.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

    别名

    CD172b

    背景

    Signal regulatory protein beta 1,CD172b, the signal-regulatory protein beta (SIRP beta) is a disulfide-linked homodimer expressed on myeloid cells including monocytes and dendritic cells. Similarly to CD172a, it serves as a negative regulator of tyrosine kinase-coupled signaling processes. Unlike CD172a, the CD172b protein does not possess the cytoplasmic domain, but instead its transmembrane domain can interact with another transmembrane protein DAP-12, which contains ITAM sequences in its intracellular domain and links CD172b to the downstream signaling molecules. The result is e.g. regulation of neutrophil transepithelial migration.,SIRPB1

    基因ID

    10326

    UniProt

    O00241
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